1. Military Medical Academy – Sofia, Scientific Institute for Emergency “N. Pirogov” – Sofia; Exposé of a final report entitled „Methods of nutritional therapy – mixed parenteral and enteral nutrition“ adopted by protocol ? 23/1012.1986 by the Scientific Council of the Higher Military Medical Institute – Sofia, Bulgaria
2. Central Experimental Laboratory for production, implantation and design; Contract with Institute for Emergency „Pirogov“ – Sofia for delivery of Biostim – bioproduct for enteral nutrition
3. Central Experimental Laboratory for production, implantation and design; Patent Library AIS „SIREN“, reg. ? 82307019, Report on: “Development of Food for enteral feeding based on freeze-dried lactic acid lactose-free products“, stage II, 3 “Study of amino acid and salt composition of food, a proposal to use the results in practice”
4. Military Medical Academy, Institute for Emergency „N. Pirogov“, Central Experimental laboratory for production, implantation and design; Patent Library AIS „SIREN“, reg. ? 82307019, Final Report on: „Diagnosis and treatment of multiple organ deficiency“, Program task: Development and clinical testing of food and means for enteral feeding on the basis of lyophilized lactic acid lactose-free products
5. Ministry of Health, Institute for Emergency „N. I. Pirogov“; Protocol for the clinical testing of a lyophilized lactic acid product „Biostim“ produced by „Central Experimental Laboratory for production – implantation – design“ at SO „Dairy Industry“ Sofia
6. Military Medical Academy, Institute for Emergency „N. Pirogov“, Central Experimental laboratory for production, implantation and design; Patent Library AIS „SIREN“, reg. ? 82307019, Final Report on: „Diagnosis and treatment of multiple organ deficiency“, Program task: Development and clinical testing of food and means for enteral feeding on the basis of lyophilized lactic acid lactose-free products
7. Military Medical Academy, Medical University – Sofia, National Center of Hygiene, Ecology and Nutrition, Medical University of Würzburg – Germany, Elbi Bulgaricum JSC; Research topic: Complex medico-biological studies of the effects of Biostim LBS on prophylactic and healing processes in people put to extreme strain in sea rescue operations, pilots and navigators from the Air Force and in people with acute and chronic drug damages
8. National Center of Hygiene, Ecology and Nutrition, Medical University of Würzburg – Germany, Military Medical Academy, Medical University – Sofia, SF Elbi; „Complex medical-biological studies in a prolonged vestibular load in case of a shipwreck“; Aim – study of the effect of the prolonged vestibular load and the other experimental sea factors on the body and approbation of the lactic acid product of SF Elbi – Biostim LBB as food with which rescue vehicles in water and air transport can be equipped
9. Command of the Air Force and the Medical Department at the Headquarters of the Air Forces, Air Hygiene Laboratory to OAMNII – MMA; Finding for a study of two lyophilized lactic acid products „Bulgaricum with pectin“ and „Biostim with pectin“, developed on the basis of specific strains of Lactobacillus bulgaricus – manufacturer SF „ELBI ENGINEERING“ – SOFIA; Aim of the task: depending on the results of the study to include these two products in the ration of the flight crews of the Air Force
10. Written statement for the clinical testing of the effect of „Biostim LBB“ on the recovery process in cases of different intoxications in the Clinic of Toxicology and Allergology – MMA Sofia and Clinic of Toxicology – Naval Hospital – Varna
11. Military Medical Academy – Sofia, Department of Toxicology and Allergology at the Higher Military Medical Institute – Sofia, Clinic of Toxicology and Allergology at the Naval Hospital – Varna; Exposé of the protocol for a clinical testing of a low-lactose lactic acid product Biostim LBB in the treatment of patients with various intoxications
12. Contract between Meiji Milk Products Tokyo, Elbi Bulgaricum JSC and Prof. N. Alexandrov for a study on: Complex medical biological studies of the effects of Biostim LBB on lipid metabolism and immune system in people put to extreme mental and physical stress
13. Report of Gen. Major Ass., N. Alexandrov, Ph.D., Col. Dr. R. Zlatev and Col. Dr. V. Minkov to the Command of the Air Force concerning further development of the scientific topic studying the effect of the lactic acid product „Biostim LBB“ on the lipid metabolism and the immune system in pilots and navigators
14. Military Medical Academy, United aero-medical Research Institute, Department of Toxicology and Allergology; Exposé of protocol and scientific articles for a clinical study of the effect of the bioproduct Biostim LBS-1 on pilots and navigators from Air Force of the Republic of Bulgaria
15. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; University Hospital „St. Anna – Varna“ JSC, Hospital Pharmacy; Clinical Laboratory, Hospital „St. Marina“ – Varna; Department of Nephrology, Haemodialysis and Toxicology, Hospital „St. Marina“ – Varna – Study of the effects of „Biostim LBS“ and silymarin on an experimental model of carbon tetrachloride induced hepato-toxicity in rats
16. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; University Hospital „St. Anna – Varna“ JSC, Hospital Pharmacy; Clinical Laboratory, Hospital „St. Marina“ – Varna; Study of the effect of the probiotic Biostim LBS on the lipid metabolism
17. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of General and Clinical Pathology, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; University Hospital „St. Anna – Varna“ JSC, Hospital Pharmacy; Clinical Laboratory, Hospital „St. Marina“ – Varna; Study of the effect of the probiotic Biostim LBS in experimentally induced hyperlipidemia
18. Medical Faculty – Sofia, Department of Pharmacology; Written statement for a comparative pharmacological and biochemical study of the effects of Laktera, Laktera/Panax and Laktera /Hypericum on ulcer formation and ethanol-induced oxidative stress in rats
19. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of General and Clinical Pathology, Medical University – Varna; Protective effect of the probiotic Biostim LBS in a model of indomethacin-induced ulcer-genesis
20. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of Pathophysiology, Medical University – Varna; Department of Anatomy, Histology, Embryology, Medical University – Varna; Effects of the probiotic Biomilk on indomethacin-induced oxidative damage of some tissues
21. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University -Varna; Department of General and Clinical Pathology, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; Effect of the probiotic Biostim LBS on histopathological changes in liver in experimental hypercholesterolemia
22. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of General and Clinical Pathology, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; Hepato-protective effect of the probiotic Biostim LBS on experimental model of carbon tetrachloride-induced hepatotoxicity in rats
23. Department of Preclinical and Clinical Pharmacology and Biochemistry, Medical University – Varna; Department of General and Clinical Pathology, Medical University – Varna; Department of Toxicology and Allergology, MMA – Sofia; Department of Radiology, Medical University – Varna; Ray-protective effect of the probiotic Biomilk containing Lactobacillus bulgaricus
24. Abstract of Dissertation of Daniela Petrova Peneva for conferment of an educational and scientific degree „Doctor“
25. Abstract of Dissertation of Marieta Petrova Georgieva for conferment of an educational and scientific degree „Doctor“
26. Statement of Colonel Dr. Vencislav Minkov Minkov, Head of „Medical Department“ at division 22800 to the Chief of the General Staff of the Air Force for a study of two products – Bulgaricum with pectin and Biomilk with pectin used by pilots from the Air Force
27. MMA, An extract from the minutes from Vice Head of MMA for educative and scientific affairs, Ass. Prof. Dr. A. Andreev on ongoing clinical tests of low-lactose dry milk products with trademarks „Biomilk“ and „Laktera“
28. An opinion of the Head of the Department of Toxicology and Allergology at the Military Medical Academy – Sofia, Prof. Dr. Nikola Alexandrov Ph. D., about replacing yogurt with wholefood supplement with probiotic effect Biomilk and Biostim in conditions harmful for health.
29. Certificate of MMA to give “Biomilk” and “Laktera”, produced by Daflorn Ltd., as wholefood supplements and functional food to the contingent of the Bulgarian Army. And their use in Military Medical Academy for more than 10 years as a food therapy of seriously ill and operated patients.
30. MMA, Head of the Clinic of Toxicology and Allergology, Associate Dr. N. Alexandrov; Recommendation for the use of probiotics in cases of serious toxicological and allergic diseases (Epidermolis necroticans bulosa Syndrome), as well as in other cases of toxicological and allergic diseases with beneficial effect.
31. MMA, Head of the Clinic of Toxicology and Allergology, Associate Dr. N. Alexandrov; Protocol for the use of the products from the series „Biomilk“ and „Biostim“, containing Lactobacillus Bulgaricus
32. MMA, Deputy for the health affairs of MMA, Ass. Prof. Ramshev; Recommendation for the use of different probiotics with trademark Biomilk and Laktera with a beneficial effect in patients requiring stimulation of the immune system of the body because of different viral or bacterial diseases.
33. Statement of the Ministry of Labour and Social Affairs to the Ministry of Health and the General Headquarters of the branch syndicates – Proposal to include the wholefood supplement Laktera in the nomenclature of the antidotes and protective food
34. Recommendation from Alexander Chakmakov, Ex. Director of „Titan Zlatna Panega Cement“, JSC for the benefit of the probiotics Biomilk and Laktera as a protective food
35. MMA, Certificate for clinical tests and Certificates of Analysis of the probiotic wholefood supplements Biomilk, Laktera and Magic Power.
36. Certificate of MMA to give “Biomilk” and “Laktera”, produced by Daflorn Ltd., as wholefood supplements and functional food to the contingent of the Bulgarian Army located in Iraq. As well as their use in the Military Medical Academy for more than 10 years as a food therapy of seriously ill and operated patients.
37. Full Doping control of the product series Biomilk in German Sports University of Cologne – Doping Laboratory
38. Ukrainian Research Institute of Medical Transport, State Department of maritime and river transport of Ukraine, Medical University – Varna – Effects of Biomilk Hepanorm in simulated shipwreck
39. Journal „Medicine and Health“ – „Ray-protective effect of a lactic acid product containing a Lactobacillus bulgaricus strain“
40. Annual book of IMAB for Bulgaria, Israel, Germany, Norway, France, Italy and USA – Study of the probiotic Biostim for teratogenic effect
41. International Conference in Lyon – Lactic acid fermentation and biotechnological method of obtaining a low-lactose lactic acid product for special diets and therapeutic food
42. Journal „Biotechnology“ – „Effect of the low-lactose lactic acid products Bulgaricum and Biostim on the immune system“
43. National Cancer Center, National Centre of Haematology and Transfusiology; Study of the ray-protective effect of Gerisan and Biostim LBS on the basic leukocyte populations in cases of radiotherapy of cancer.
44. Balkan Military Medical Committee; The 4th Congress of B.M.M.C.; June 6-10, 1999, Bucharest, Romania; EFFECT OF THE BIOSTIM LBB YOGHOURT-TYPE PRODUCT ON LIPID METABOLISM IN AIR-FORCE AVIATORS; Author(s): Alexandrov, N., Petrov, A., Zlatev, R., Zhekova, M., Mikhaylova, Z., Kotseva, M. and Alexiev, L. Institution: Military Medical Academy, Sofia Institution For Aviation Medicine;
45. FEBS; 20th MEETING OF THE FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES, organized by the Hungarian Biochemical Society; Budapest, Hungary, August 19-24, 1990; Freeze dried dietetic lactic acid product “Biostim LBS”; Gyosheva B., Alexandrov N., Ivanova P., Manafova N., Georgiev G.; Central Exper. Lab. Dairy Ind. 1618 Sofia; Emergency Inst. “N. Pirogov” 1612 Sofia, Bulgaria.
46. An International Journal for the Rapid Publication of Short Reports on Biochemical Mechanisms of Mammalian Toxicity; Clinical Research on the Victims of Chemical Accidents in Bulgaria; N. Alexandrov, D. Jordanova and M. Georgieva, Military Medical Academy, Sofia, Bulgaria; VI INTERNATIONAL CONGRESS OF TOXICOLOGY, Rome, 28 June – 3 July 1992
47. Therapeutic Drug Monitoring; A Journal Devoted to Therapeutic Drug Monitoring and Clinical Drug Toxicology, volume 15, number 2, 1993, Philadelphia, USA; Influence of Nootropic Agents and Hyperbaric Oxygenation in the Treatment of Acute Poisonings with Halogenated Hydrocarbons; N. Alexandrov, M. Georgieva, Military Medical Academy, Sofia, Bulgaria.
48. Addictive drugs and addictive states, The state of the art; Addiction Research Foundation of Italy (ARFI), Padova in collaboration with University of Florence – Department of Preclinical and Clinical Pharmacology “Mario Aiazzi Mancini”; International congress of Toxicology in Florence, 07.1992; Clinical research on narcotic and non-narcotic drug addiction. Comparative analysis; N. Alexandrov, M. Georgieva, D. Jordanova.
49. Biotechnology Journal; “Biostim LBS – a special diet and therapeutic low-lactose powdered product”, issue 4, series V, 92 – english version. Biostim LBS – a special diet and therapeutic low-lactose powdered product; B. Gyosheva, N. Alexandrov, N. Manafova, P. Ivanova, G. Georgiev; ELBY Engineering –G, Sofia and Military Medical Academy, Sofia, Bulgaria.
50. Biotechnology Journal, 2/1994; Effect of dairy products, containing Lactobacillus strain LBL4 on some biochemical parameters in humans; M. Zhekova¹, K. Avramova², B. Gyosheva³; Aviomedical Research Institute, Higher Medical Academy, Sofia; National Center of Hygiene, Medical Ecology and Nutrition, Sofia; ELBY Engineering-G, Sofia.
51. Biotechnology Journal, 4/1992; Biostim LBS: a special diet and therapeutic low-lactose powdered food product; B. Gyosheva, N. Alexandrov, N. Manafova, P. Ivanova, G. Georgiev; ELBY Engineering – G State Company, Sofia; Military Medical Academy, Sofia.
52. Cancer Letters Journal 114 (1997) 93-95; Preventive role of lyophilic dairy products bulgaricum and biostim; T. Ivanova, M. Jekova; Transport Medical Institute, Sofia, Bulgaria; Medical Military Aviation Institute, Sofia, Bulgaria.
53. Contract between Joint MLB Promotion Planning Committee between MEIJI MILK, Tokyo and LB Bulgaricum PLC, Sofia and Prof. Nikola Georgiev Alexandrov D.Sc. – Head of Toxicologic and Allergologic Department at Military Medical Academy; Clinical-Immune Researches over some effects of the yoghurt product “Biostim LBB” on pilots from the Army-Air Forces; N. Alexandrov¹, K. Plotchev², K. Penkova², R. Vladimirova², K. Mladenov², P. Zlatev³, Dzh. Nedyalkova; ¹ Military Medical Academy, Sofia – CLINIC OF TOXICOLOGY; ² Military Medical Academy, Sofia – CENTRAL LABORATORY ON CLINICAL IMMUNOLOGY; ³ OAMNII, Military Medical Academy, Sofia.
54. Fundamental & Clinical Pharmacology; The 3rd Meeting of the Federation of the European Pharmacological Societies (EPHAR); 6-9 July 2001, Lyon, France; Effects of the chronic dietary supplementation of the probiotic Biostim LBS on carbon tetrachloride-induced hepatotoxicity in rats; K. Marazova¹, N. Alexandrov², ¹Department Pharmacology Toxicology, Medical Faculty, Sofia, Bulgaria, ²Department Toxicology Allergology, Military Medical Academy, Sofia, Bulgaria.
55. Journal „Medicine and Pharmacy“, issue 2 / 2002, „Clinical features and treatment of acute intoxications with heroin”
56. Journal „Medicine and Pharmacy“, issue 4 / 2003, „Treatment of organophosphorus pesticides poisoning“
57. „Medicine and Pharmacy“, issue 2 / 2003, „Study of the probiotic Biostim LBS in experimentally induced hyperlipidemia“
58. VIIth National Congress of Nutrition with International participation; Nutrition science for human health protection; Varna – St. Konstantin and Elena, Bulgaria, May 15-17, 2003; Probiotics application before and in the early post-operative period; Alexandov G., D. Damianov, Clinic of Surgery, UNBAL “Queen Jovana” – Sofia
59. NATO Symposium; May 2005, Munich, Germany; Complex treatment of organophosphorus pesticide poisoning as a model of chemical warfare agents; Alexandrov N., Ks. Stoyancheva, Military Medical Academy, Toxicology Department.
60. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005 ; The application of probiotics for restoration of vaginal environment; Stefan Kovachev¹, Aneta Nacheva¹, Daniela Petrova², Milena Kovacheva²; ¹MC “Gynart” MMA – Sofia; ²MC “Evrozdrave” MMA – Sofia
61. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005; Farmacological study of the probiotic Biomilk, containing Lactobacillus bulgaricus, for antioxidant activity, Georgieva M.¹, Bekyarova G.², Alexandrov N.³, Manolov N.?; ¹Department of preclinical and clinical pharmacology and biochemistry, Medical University “Prof. Dr. Paraskev Stoyanov” – Varna, ²Department of Pathophysiology, Medical University – Varna, ³Department of toxicology and allergy, MMA – Sofia, ?Clinic of Vascular Surgery, University Hospital “St. Anna” – Varna
62. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005; Good bacteria of Bulgarian youghurt – a base of symbiotic and functional food, Alexandrov N.¹, Gyosheva B.², Ivanova P.³; ¹Military Medical Academy, ²Bulgarian Association of Dairy Processors, ³LB Bulgaricum
63. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005; Probiotics – base of functional nutrition and nutritive treatment of XXI century; Nikola Alexandrov¹, Phd, Daniela Petrova², Milena Kovacheva¹; ¹Emergency Clinic of Toxicology and Allergy, MMA – Sofia, Bulgaria, ²MC “Evrozdrave” MMA Sofia, Bulgaria
64. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005; Probiotics – lifestyle, M. Georgieva¹, E. Softova², P. Borisova, N. Alexandrov³, N. Manolov?; ¹Department of preclinical and clinical pharmacology and biochemistry, Medical University “Prof. Dr. Paraskev Stoyanov” – Varna, ²Department of General and Clinical Pathology, Medical University “Prof. Dr. Paraskev Stoyanov” – Varna, ³Department of Toxicology and Allergy, MMA – Sofia, ?Clinic of Vascular Surgery, University Hospital “St. Anna” – Varna
65. International Symposium on original Bulgarian yogurt under the patronage of President of the Republic of Bulgaria, Sofia, 2005; Synbiotics – their place in modern treatment of abusers, Daniela Petrova¹; Milena Kovacheva²; ¹MC “Evrozdrave” – MMA, Sofia, ²Clinic of Emergency Toxicology and Allergy, MMA – Sofia
66. Journal „Military Medicine“, issue 4 / 2007, „Study of the antioxidant activity of the probiotic Biomilk under experimental conditions“
67. Journal „Military Medicine“, issue 2 / 2007, „Ray-protective effect of the probiotic Biomilk“
68. Journal „Medicine and Pharmacy“, issue 9-10, „Alcoholic disease, clinic and treatment“
69. Journal „Medicine and Pharmacy“, issue July/ 2008, „Probiotics and vaginal flora”
70. Journal „Medicine and Pharmacy“, issue 1 / 2009, „Prevention and treatment of atherosclerosis with probiotic lactic acid food and bacteria“
71. EXPERIMENTAL CLINICAL STUDY OF THE EFFECT OF THE PROBIOTIC BIOMILK IN CASES OF LIVER INJURIES; VI National Congress of Pharmacology 2009; Georgieva M.¹, Popov G.², Plochev K.², Alexandrov N.²; ¹ Department of Preclinical and Clinical Pharmacology and Toxicology, Medical University of Varna; ² Military Medical Academy
72. Effect of a probiotic product with Lactobacillus bulgaricus DWT1 in avoiding adverse effects during adjuvant treatment of patients with tumors of the stomach, colon and rectum. Medical University, Zagreb, Republic of Croatia, Pimezon Polyclinic; Prof. Dr. Mirko Shamija; December 2012
73. Forensic Medicine 9/2013, A meta-analysis of the effects of a probiotic product with Lactobacillus bulgaricus Laktera in the gastrointestinal tract; Ramshev C. 1 D. Alexandrov 1; 1 MMA Sofia
74. MU Varna power. Magazine., 2013, Effect of probiotic product Laktera Vision with Lactobacillus bulgaricus and bilberry extract on syndromes dry and tired eyes Georgieva M.1 Alexandrov D.2; 1 MU Varna, 2 Sofia MMA
75. World Congress of probiotics Athens 2014, newly origin of probiotics in the Balkans; Petrov N.1 G. Alexandrov 1 Peneva M. 2; 1 MMA Sofia 2Plovdiv University of Plovdiv
76. Bulgarian Red Cross 2014 Recommendation on the use of probiotic foods Laktera of victims of disasters and accidents.
77. World Journal of Pharmacy and Pharmaceutical Sciences, volume 4, issue 06, 2015q 130-136, Antiproliferative Effect of Bulgarian Spring Water Probiotics (Laktera Nature Probiotic®) Against Human Colon Carcinoma Cell Line, Kaloyan Georgiev, Marieta Georgieva, Ivan Iliev, Maria Peneva, Georgi Alexandrov; Department of Preclinical and Clinical Sciences, Sector Pharmacology and Toxicology, Faculty of Pharmacy, Medical University Varna; Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Sofia; Medical Centre Evrozdrave Sofia; Military Medical Academy Sofia.
78. 6th Southeast European Conference of Chemotherapy, Infectious and Cancer Diseases, November 2015, Thessaloniki, Greece; Anti-tumor Effect of probiotics – experimental and clinical research, Georgi Alexandrov, Kaloyan Georgiev, Marieta Georgieva, Ivan Iliev, Maria Peneva; Military Medical Academy Sofia; Department of Preclinical and Clinical Sciences, Sector Pharmacology and Toxicology, Faculty of Pharmacy, Medical University Varna; Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Sofia; Medical Centre Evrozdrave Sofia.
79. 3rd Biennial Conference of Probiotic Association of India (PAi), International Symposium on Stress, Microbiome & Probiotics, March 11-13, 2016, NISER, Bhubaneswar, India; Application of Lactobacillus bulgaricus in Clinical Practice; Georgi Alexandrov, Maria Peneva; Military Medical Academy Sofia; Medical Centre Evrozdrave Sofia.
80. Excerpt from Abstract of dissertation, Sofia 2016, p. 27-29; Epidemiological study of patients with food allergies; Maria Peneva, Medical Centre Evrozdrave Sofia.
81. Scripta Scientifica Pharmaceutica, ISSN 2367-6000, volume 4, 2017, supplement 2, page 51, Medical University Prof. Dr. Paraskev Stoyanov, Varna, Bulgaria, “Hepatoprotective effect of probiotic food, containing lactobacillus bulgaricus DWT1 in acute ethanol intoxication in experimental animals”, Gabriela Kehayova1 , Marieta Georgieva, Kaloyan Georgiev, G. Aleksandrov, M. Peneva.
82. World Journal of Pharmaceutical Research, volume 7, Issue 12, 2018, Research Article, page 35-42, “Hepatoprotective effect of probiotic, containing Lactobacillus bulgaricus DWT1, in acute paracetamol-induced liver damage in rats”, Gabriela Kehayova, Marieta Georgieva and Kaloyan Georgiev, Medical University, Varna
83. Monography, Varna 2018, publishing house Steno, pages 167, “Probiotics – Medicine and Food”, Marieta Georgieva
84. Journal of Functional Foods, Volume 56, May 2019, Pages 232-245, “A probiotic formulation containing Lactobacillus bulgaricus DWT1 inhibits tumor growth by activating pro-inflammatory responses in macrophages”, Dipanjan Guhaa, Arka Banerjeea, Raktim Mukherjeea, Biswaranjan Pradhana, Maria Peneva, Georgi Aleksandrov, Sujit Suklabaidya, Shantibhushan Senapati, PalokAich,
85. Probiotics in the Prevention and Management of Human Diseases,Academic Press, 2022, Pages 431-448, Chapter 29 – Probiotics: past, present, and future challenges, Marieta Georgieva, Kaloyan Georgiev, Nadezhda Hvarchanova,
86. Educational event III international science conference “Human microbiota” FSBSI “Institute of experimental medicine”, October 7-8, 2021, St. Petersburg, “Newly found origin of probiotics in the Balkans” , Nikolai Petrov, Georgi Aleksandrov, Maria Peneva
87. National Conference on Clinical Toxicology with International Participation on “Toxicology Today“ June 2-4, 2022, Pleven Medical University, “Probiotics – contemporary challenges”, Marieta Georgieva, Georgi Alexandrov, Maria Peneva, Daniela Petrova
88. National Conference on Clinical Toxicology with International Participation on “Toxicology Today“ June 2-4, 2022, Pleven Medical University, “MORBUS LYELL – clinical case”, Katerina Stefanova, Evgenia Burzashka, Olimpiada Atmazhova, Ani Aleksandrova, Nadya Vasileva,
89. National Conference on Clinical Toxicology with International Participation on “Toxicology Today“ June 2-4, 2022, Pleven Medical University, “Toxic-necrotic changes after SARS-COV 19 a clinical case”, Olimpiada Atmazhova, Evgenia Burzashka, Katerina Stefanova, Ani Aleksandrova, Nadya Vasileva, Vladislav Tenev
90. 11^th National Congress of nutrition with international participation “Nutrition science with evaluation of the present and look to the future”, 2022, Bulgarian Society of nutrition and dietetics, “Antioxidant and hepatoprotective activity of probiotic food against paracetamol-induced liver damage in rats”, M. Georgieva, K. Georgiev, N. Hvarchanova, S. Stoeva, M. Radeva-Ilieva, V. Tzankova, M. Kondeva-Burdina, D. Aluani, M. Tzaneva
91. Patent No. 4294 dated 06.07.2022, registered in the Patent Office of the Republic of Bulgaria for a biologically active product used as nutritional therapy in the treatment of patients with COVID-19, including pregnant women.
92. Scientific project No. 21-00038 to study the immune- stimulating and protective effect of probiotic food Laktera in extreme stress situations during the upcoming trip, stay and return of our expedition to Antarctica on Livingston. The project is carried out by the VVMU “N. Y. Vaptsarov” together with the University of Varna and the University of St. Kliment Ohridski” for the period 2022-2023.
93. 16th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health – IPC2023, 20-22 June 2023, Bratislava, Slovakia, Application of a probiotic formula containing Lactobacillus bulgaricus DWT1 in patients with COVID-19, Maria Peneva, Ioannis Misopoulos, Evgenia Burzashka, Tsvetan Lukanov, Tsetsa Doichinova, Anna Petkova, Marieta Georgieva, Georgi Alexandrov, Pencho Tonchev, Medical Center “Eurohealth-Bulgaria”,  Sofia, Bulgaria, Mika Nutri-Pharma OOD, Petrich, Bulgaria, UMBAL Pleven “Dr. Georgi Stranski”, Pleven, Bulgaria, University Multispecialty Hospital for Active Treatment St. Anna Sofia, Sofia, Bulgaria, Varna Medical University “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
94. V International Scientific Conference ”Microbiota of Humans and Animals”, Institute of Experimental Medicine, October 11-13, 2023, St. Petersburg, Effects of Lactobacillus bulgaricus DWT1 on cell immunity in patients with COVID-19, Georgiy Alexandrov, Maria Peneva, Ioannis Misopoulos, Evgenia Barzashka, Tsvetan Lukanov, Tsetse Doichinova, Anna Petkova, Marieta Georgieva, Pencho Tonchev
95. National Clinical Toxicology Conference “Toxicology in the lens of the present and the future”, November 2-4, 2023, Bulgaria, Probiotics and modulation of cellular immunity in COVID-19, Olympiada Atamadjova, Katerina Stefanova, Ani Alexandrova, Georgi Alexandrov, Maria Peneva, Anna Petkova, Marieta Georgieva, Pencho Tonchev
96. VI International scientific conference on human and animal microbiota – HAM2024, Saint Petersburg, Russia, 14 – 16 October 2024, Anticancer effect of Lactobacillus bulgaricus DWT1 – experimental and clinical studies, Georgi Alexandrov, Kaloyan Georgiev, Marieta Georgieva, Palok Aich, Maria Peneva
97. Jubilee scientific conference with international participation “50 years of medical education and science in Pleven” 01-03 November 2024, The First Bulgarian Military Antarctic Expedition and the Effects of Lactobacillus bulgaricus DWT1 as a psychobiotic under extreme stress, Rositsa M. Nedeva, Nadezhda Sl. Vladimirova, Boyan K. Mednikarov, Petko D. Ginev, Maria N. Peneva, Georgy N. Alexandrov, Evgenia I. Barzashka
98. IV World Health Congress 2025 Prague, 3-5 October 2025, The effects of Lactobacillus bulgaricus DWT1 as a psychobiotic during the Bulgarian Antarctic Expeditions & on post-COVID syndrome , Maria Peneva, Rositsa Nedeva, Nadezhda Vladimirova, Boyan Mednikarov, Petko Ginev, Maria Yakova, Miglena Angelova, Georgy Alexandrov, Anna Petkova, Ioannis Misopoulos, Marieta Georgieva

United States Patent of Daflorn Ltd

The present invention relates to compositions containing probiotic microorganisms and methods of making and using probiotic associations containing these microorganisms. More particularly, the invention relates to an association of probiotic lactic acid microorganisms including newly identified strains of microorganisms and their use in dietary products. These microorganisms are cultured to produce a protective shell that enhances self-stability of compositions and products of the invention. The isolated microorganisms include new strains of Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus helveticus, Lactobacillus delbrueckii subsp. lactis, and Streptococcus thermophilus.

All products according to this US Patent contain original probiotic strains, isolated from pure spring water in Bulgaria. All products have approved health claim according to Commission Regulation (EU) No 432/2012 : Live probiotic cultures L. bulgaricus and St. thermophilus improve lactose digestion in individuals who have difficulty digesting lactose.

European Patent of Daflorn Ltd

Patent No: EP 3 172 973The invention relates to a probiotic formula involving cooperation of strains of probiotic microorganisms, isolated as it is, from a traditional diary product in Rhodope mountains, to a process of preparation of the probiotic formula and its use as a dietary food for people with impaired liver function and structure, for controlling the symptoms of food allergy and for recovering the normal vaginal lactobacillacae flora of women. The probiotic cooperation of strains microorganisms includes newly identified strains of Lactobacillus bulgaricus and Streptococcus thermophilus. This probiotic cooperation is used for fermentation of a standardized and pasteurized goat`s milk for preparation of the probiotic formula, which after lyophilization and storage for 24 months at a room temperature up to 24°C, contains alive cells of the probiotic cooperation, in concentration from 1.1×10⁹ cfu/g to 1.6×10⁹ cfu/g.

All products according to this EU Patent contain unique goat`s milk probiotic with original strains. All products have approved health claim according to Commission Regulation (EU) No 432/2012: Live probiotic cultures L. bulgaricus and St. thermophilus improve lactose digestion in individuals who have difficulty digesting lactose.